School of engineering in Physics, Applied Physics, Electronics & Materials
The aim of this lecture is to deliver a global overview of bioelectronic sciences and technologies. Bioelectronic is a new field of science that corresponds to the study of bioelectrical interfaces with the dual goal of i. monitoring physiological phenomena or biological species and ii. interacting with biological functions.
Bioelectronic could be divided in four main topics:
1.Molecular bioelectronic e.g. biosensors and biochips (that involve the integration of a biological function within an electronic device to assess intensive functions of the environment)
2.Cellular bioelectronic, e.g. MicroElectrode Arrays (which consist on the design of electronic systems dedicated to the monitoring and/or the stimulation of cell networks in order to investigate the collective function of, as well as the information transfer path within, these networks)
3.Medical bioelectronic, e.g. ECG, EEG electrodes, TENS, neurostimulation, retinal implants… (that deals with the design of electronic interfaces dedicated to the monitoring and the stimulation of human functions).
4.Bioinspired nanosystems in which biomolecules exhibiting selfassembly properties are used to design new electronic interfaces.
1. Introduction to Bioelectronic
a. Definition and principal approaches
b. Market positioning
c. Global « environment » of bioelectronic research and development
2. Elements of biology
a. Nucleic acids
c. From lipids and proteins to microorganisms
3. Biomolecule immobilization
a. Physi and chemi-sorption
b. Covalent binding
c. Polymers and entrapment
4. Molecular bioelectronic
a. Biosensor work and functions
b. Biochips for proteomic and genomic
c. Cell chips
5. Bioinspired nanosystems
a. Biolomolecules and self-assemblies
b. Biological selfassemblies for template design of nanomaterial
c. Bioinspired nanodevices
6. Biomedical electrodes and neuroprothetic
a. Materials for implant and transdermal electrodes
b. Impedance tomography
c. Artificial Cochlea
d. Artificial retina
Very basic knowledge in chemistry, biology and biochemistry.
Ability to understand, to integrate, vocabulary and knowledge of a science at the interfaces between biology, physics and physico-chemistry.
The exam is given in english only
Oral presentation of a scientific article coming from the recent literature.
The understanding level, criticism and projection abilities will be appreciated for the quotation
This course is given in english only