Volumes horaires
- CM 5.5
- TD 5.5
Crédits ECTS
Crédits ECTS 1.5
Objectif(s)
To understand the specificity of the irradiation of living beings by ionizing radiations. From the underlying physical principles to their biological consequences.
Topics :
- Specificity of the interactions between ionizing particles and the living matter : from physical interaction to biological responses
- Elements of radiobiology
- Initial physical events : water radiolysis, free radical formation, chemical and biological steps, DNA damages
- Dosimetry concepts : from absorbed dose to dose equivalent. Damages to living organisms. Microscopic aspects of energy deposition.
Contenu(s)
- Specificity of the interactions between ionizing particles and the living matter : from physical interaction to biological responses
- Elements of radiobiology
- Initial physical events : water radiolysis, free radical formation, chemical and biological steps, DNA damages
- Dosimetry concepts : from absorbed dose to dose equivalent. Damages to living organisms. Microscopic aspects of energy deposition.
Prérequis
Interaction between ionizing radiations or particles (photons, electrons, ions, neutrons) with the matter
Contrôle des connaissances
L'examen existe uniquement en anglais
Written exam (2h)
Examen écrit (2h)
Informations complémentaires
Le cours est donné uniquement en anglais
Cursus ingénieur->BIOMED->Semestre 5
Bibliographie
E.B. Podgorsak (editor), Review of radiation oncology physics: A handbook for teachers and students (16 chapters, 696 pages), International Atomic Energy Agency; Vienna, Austria, 2005, STI/PUB/1196 (ISBN 9201073046).
Eric Hall, Radiobiology for the Radiobiologist. 2006. Lippincott