Medical applications of ionizing radiations - 5PMBAIR8

Objectif(s)

MAIR-2 : Biological effects and medical applications of ionizing radiation

The aim of this course is to provide an overview and basic knowledge in the biological responses elicited in cells by radiation exposure, and how they are used in medical applications such as radiotherapy, in combination with immunotherapy. Thus, this course will cover the health effects of ionizing radiation, from cells to disease, and the use of ionizing radiation in new (combinatorial) radiotherapy procedures.

Contenu(s)

Specific topics of the MAIR 2 are :

• DNA damage and DNA repair (4h).
• Biological effects of radiation (4h).
• Enhancement of dose with high Z elements (3h).
  This course includes a labwork (8h) in which students will have the apply an approach based either on molecular biology or on immunochemistry/cellular imaging to analyze the consequences of ionizing radiation exposure in human cells

Previous knowledge in basic biological mechanisms and basic experience in biological experiments