Physiology and Bioenergetics - 4PMBPBI6

Objectif(s)

To provide an overview of the pathways by which metabolic substrates are absorbed, stored, and used by the human organism in physiological and pathophysiological conditions.

Contenu(s)

Following an introduction regarding macromolecules composing living systems and the main biochemical reactions involved in energy production, the physiology of the liver, adipose tissue, and skeletal muscle will be described as well as their roles in bioenergetics. Physiological (exercise) and pathophysiological (type I and II diabetes) variations of bioenergetic metabolism will then be studied in details. Finally, cardiovascular physiology will be described as well as the main pathophysiological mechanisms of cardiovascular diseases.

None – all required concepts will be delivered over the course. However, a background in cellular biology might facilitate the assimilation of the 1st part of the course (Introduction, see above), which is crucial for an in-depth understanding of the subsequent physiological and pathophysiological developments.